Tag Archives: anti-inflammatory diet

The voice of authority

I’m going to bang on, again, about not believing everything you read online.  I know I’ve talked about it before, several times, but it’s worth repeating because when we’re sick we get desperate and when we’re desperate our logic and reasoning can go out of the window.

Some people write with such conviction and authority that they make you question your own mind.  Even cynical old me sometimes reads a comment or a blog post and thinks “hmmm, maybe I should give up gluten after all” even though I know fine well I don’t have a problem with it.  It’s particularly easy to get sucked in if the article ends with research references, after all the author has obviously based their information on evidence.  Or have they?

I try to be savvy about what I read online and I question everything.  In particular I:

  • Learn about the author.   If they are talking about health issues I need to find out if they are a qualified health professional.  If they are talking about science such as genetics or the basis of disease I find out if they are a qualified scientist or researcher.  If they are offering dietary information I find out if they are a qualified nutritionist.
  • Discover their bias.  I have EDS, MCAD, M.E. and Endometriosis, so when I read about people with similar sounding symptoms to me I automatically think they have what I have.  But here’s the thing: I don’t know them from Adam.  I don’t have access to their medical records.  I don’t know what tests they’ve already had done and which diseases they’ve had ruled out.  I am hugely biased because of my own experience, but my experience may not be someone else’s experience.
  • If they include research references read them.  Their reference may be to one unpublished paper written 50 years ago, in which case it is irrelevant.  Fact is only fact when it is unbiased, been conducted in a controlled environment (ie all participants of the research have the same disease, have been measured against either healthy controls or controls with another disease, and the same testing method has been applied to everyone), has been replicated by another doctor or lab, the outcome has been properly scrutinized by other experts in the field (usually through publication in a medical journal) and, most importantly, the research has been conducted on people not rodents.  If this hasn’t happened it is theory, not fact. I believe with total conviction that I am the best blogger in the whole wide world, but my belief doesn’t make it true 😉
  • If you read an article that you feel resonates with you, google the opposing view.  If you read something on inflammatory foods which you find interesting, try googling “debunking anti-inflammatory diets” and read some of the opposing opinions and more importantly facts (I don’t need to add from reliable, medical sources such as the National Institutes of Health or PubMed).

There are several areas which currently really bother me when it comes to pseudo-science and wild claims, including:

  • Genetics.  People without any scientific or medical background write a lot about genes online and they sound really convincing.  But Dr Afrin in the chapter on genetics in his book on MCAD sums up well our current position when it comes to the world of genetics and it’s this.  “The truth is, we really don’t yet know what 99.99% of this stuff truly means………..Diseases are complex systems, each with many, many interlocking/interacting phenomena and to think one can understand the entire system by knowing merely a few tiny parts of it is the height of naiveté.”  So bear that in mind the next time you read stuff online about c-KIT and Methylation from some convincing author without a single medical or scientific qualification or access to a laboratory let alone human DNA.
  • Food, in particular gluten, dairy, sugar, “plant-based diets” (so long as the plant isn’t wheat, rye or barley) and “anti-inflammatory” foods.  My regular readers will know all the pseudo-scientific crap proliferated online about food and its role in health and disease drives me to absolute distraction.  Please be more savvy about what you read and believe online and balance this with the opposing view before making any decisions about what you eat.  Jeff Schweitzer, Scientist and former White House Senior Policy Analyst with a Ph.D. in neurophysiology, makes some valid points about inflammation in this blog post for example.  I categorically state that my pages about low histamine food on my blog are based on my own experience and not fact.  I actually takes pains to point out there are NO reliable low histamine food lists online or anywhere else and very little research has been conducted on the histamine content of foods.  If a website contains a low histamine food list you need to be asking where the list has come from, the testing which was carried out to determine the level of histamine, by which methods, if it was replicated by another lab and if the data is publically available to view.  Good luck with finding a single website containing this information because I guarantee you it doesn’t exist.

The reason we lose our reason and have a tendency to believe the unbelievable, is that we’re desperate.  Sick, exhausted, baffled, frustrated, angry, lost and/or frightened.  We want someone, anyone, to tell us what’s wrong with us and how to put it right but sadly life isn’t that simple.  Patients online, persuasive and passionate as they may be, don’t know more than the leading doctors and researchers in the world on their chosen subject, however much they delude themselves that they do.  And currently, researchers in the fields of EDS, M.E. and MCAD freely admit they don’t have the answers.  They’ve recently found some interesting things, which may or may not be part of the puzzle of our diseases, and there are exciting developments in the pipeline but no-one has reached any definitive conclusions as yet, hard as that is to hear.

The one thing I know for sure is that the answers to my health issues aren’t going to come from Bob Smith in Nebraska who has no medical or scientific qualifications yet proclaims from his sick bed that he knows something the leading physicians in the world do not and that the answer to all our ills lies in methylation/a paleo diet/an anti-inflammatory diet/ingesting worms/the vagus nerve/[insert your next wildly unproven theory here].  In fact, that Bob Smith even thinks he knows more than the leading brains in the international scientific world is bonkers yet we, the reader, often believe the Bobs of this world – the stranger on the Internet we know absolutely nothing about – without even questioning or challenging them.  But we need to.





Research trends

I’ve mentioned recently my frustration at the current research trend in the M.E. world to focus on energy production when, as a sufferer, I know that the ‘fatigue’ (for want of a better term) I experience is merely a symptom of immune activation not the root cause of my disease. Researchers have been studying energy production, in particular the mitochondria, as a cause for M.E. for over 20 years now and still haven’t found anything, which leads me to conclude there is nothing to find.  I’m not suggesting that mitochondrial dysfunction isn’t part of the disease picture but it’s definitely not the cause.  I wish these people would talk to patients more, especially we old timers who’ve lived with the illness for decades!

I’m equally unconvinced by the current trend to put every ailment known to man down to gut issues (SIBO, flora, bacteria etc) – it just feels like the current ‘hot new thing’ in a very long line of ‘hot new things’ on which to pin disease.  My Dad excitedly kept an article out of his newspaper for me this week which touted “answer to chronic fatigue syndrome found in the gut” and, much as I love him, I just sighed.  Here’s the thing: most cases of M.E. start with some kind of viral or toxic event (OP poisoning, vaccinations) but the event is different in all of us – mine was a tummy bug, yours might have been glandular fever, someone else’s a Hep B vaccine.   If we’d all started with a tummy bug then I’d be much more open to the disturbed gut theory, but we didn’t.  The one thing we share is immune activation, so for me the answer has to lie in the immune system and in particular its response to viral or toxic trauma.  As I’ve said before, if researchers studied why people with the flu are so weak and exhausted they can barely get out of bed they’d go a long way to finding out the cause of M.E.  In fact, it gobsmacks me that no-one has looked at that before now!

No offence to my American friends, but there is a mould trend going on in the States with everyone convinced that mould is the root cause of their issues and it makes me want to chuckle.  Northern England is wet for 10 (sometimes 12) months of the year, humid in summer, we mostly live in houses which are at least 100 years old and inherently damp, so I’m sure mould is everywhere.  We couldn’t escape it if we tried.  Yet not every Brit you meet is sick and we don’t have a larger M.E. population than any other country as far as I’m aware.  Obviously rampant mould growth, where you have black stuff growing on your ceiling, is hazardous to health and must be dealt with but other than that we in the UK don’t give mould a second’s thought – it’s been around a lot longer than we have and as a species we’ve managed to survive.

I’m just as cynical about the current inflammatory trend.  Inflammation, it seems, is everywhere and is causing total havoc.  Only of course it’s almost impossible to measure inflammation or to say, if inflammation is present, why it’s there and whether it’s a good thing or a bad thing.  When we cut ourselves the wound is immediately inflamed which is a painful, but absolutely necessary, part of our body’s response and vital for healing.  And before anyone comments, yes I know there’s a difference between acute and chronic inflammation but who’s to say chronic inflammation isn’t just as protective as acute?  It’s got to be there for a reason and we’d do better to find out why our bodies are enlisting our inflammatory response, rather than blaming the inflammation itself.

Going off-topic slightly, the trend of foods purportedly giving you every disease from cancer to Alzheimer’s drives me insane.  We have no idea what causes Cancer and even less idea what causes dementia, so for anyone to say “burnt sausages give you cancer” or “broccoli reduces your risk of Alzheimer’s” is absolutely absurd and makes me furious.  In fact, I’d go as far as to say researchers who tout this nonsense should be prosecuted.  The same goes for anti-inflammatory foods.  If we have no accurate way of measuring inflammation, how do we know what foods affect it?!

There have been articles in the newspaper this year saying “exercise staves off dementia” and “lack of sleep increases risk of dementia” and I think “what a crock of shit!”  My Dad, who is 78, still walks 8 miles a week up a mountain and, as a former marathon runner, has exercised vigorously his entire life.   He’s never had insomnia and sleeps 9-10 hours a night without a problem, yet has dementia.  My Mum, on the other hand, hasn’t exercised since she was a child and wakes at least twice a night every night, yet she is totally mentally on the ball (when she’s not drunk!).  All these articles do is play on people’s emotions.  We don’t have a clue what causes Cancer or Alzheimer’s and that lack of control scares us, so we focus on what we eat or how much we exercise because those are two things we can control and it makes us feel better.

I’m no psychologist, but much of the information currently touted as being bad for our health, or good for our health, is environmental – sleep, exercise, food and living conditions.  In other words, all things we can control.  We’re extremely fearful of the fact that Alzheimer’s or Cancer might be viral, bacterial, or genetic, or even worse some novel new thing we as yet know nothing about, and therefore outside of our control.  We’re fairly arrogant us humans and think that we have power over our bodies, when in fact life is mostly just random and shit simply happens.  If keeping mentally alert staves off Alzheimer’s how come author Terry Prachett developed it in his 50s?  If the phytoestrogens found in soya stave off breast cancer how come soy munching vegetarian Linda McCartney died from the disease?  How come my Mum, a lifelong smoker, couch potato and current alcoholic, is nearly 80 and has never had cancer and her non-smoking, tea-total, bike riding sister died from it?  None of it makes sense and that’s the very thing that scares us the most.


Gulp.  I’ve mentioned the I word.  It’s scary.  Anti-inflammatory diets are all the rage, and just like the Paleo camp and the Gluten-free camp anti-inflammatory diet enthusiasts can be a fanatical bunch who don’t like their views questioned.  But you all know me by now, ever the one to stick her head above the parapet.  *Deep breath*

I’m quite cynical when it comes to diet curing all ills, despite the fact I’m on a restricted diet myself.  I’m no expert on inflammation so I try to look at both sides of the argument – if I google “anti-inflammatory diet benefits” I also google “debunking anti-inflammatory diet”, which not many people embarking on the diet tend to do for themselves.  They’re sick and in pain and they want to believe it will work, which I totally understand having been there myself.

There is shed loads of information online about anti-inflammatory foods and how eating such foods will cure everything from cancer to acne (in which case I’ve no idea why we poison people with chemotherapy – why not just feed them a wheelbarrow load of kale every day instead?).  What few of these sites tell you is that inflammation isn’t a single bodily event with a single cause: there are various types of inflammation, causing a range of symptoms, affecting a range of bodily systems and from all sorts of causes.  And not all inflammation is bad – shocker I know!

If you get strep throat your immune system leaps into action, inflammation being one of the symptoms caused by the immune response to bacteria, infection or trauma.  Inflammation is a vital part of the healing process and we wouldn’t live very long without it.  Nothing you eat, or don’t eat, is going to affect this type of acute inflammation which is a very good thing or people who lived on pizza and coke would be in serious trouble every time they cut their fingers.

Problems arise when inflammation becomes chronic, such as in Crohn’s Disease, or causes widespread and systemic damage like in Arthritis.  But even in chronic inflammatory diseases the inflammatory pathway is different depending on the illness, eg. the inflammation in coronary heart disease is different to the inflammation in cancers, is different to the inflammation in Arthritis, is different to the inflammation in allergy induced Asthma, which is one of the reasons why we don’t give the same drugs to allergy patients that we give to cancer patients.

Many people with mast cell disease follow an anti-inflammatory diet the reason being that when mast cells degranulate or leak, the chemicals (or mediators) they release are those involved in inflammation.  I can totally understand the logic, but there is no research to back the claims up that eating particular foods will tackle this type of inflammation as far as I could find.  From my own personal experience I’ve had all the usual inflammatory markers measured, eg. ESR, CRP and PV, and they’ve all been absolutely normal.  In addition I’ve had my poop measured for inflammation and absolutely nothing showed up.  Having said all that, I have chronic gastritis (ie stomach inflammation) – now why didn’t that show up on the blood tests?!

Mast cell disease isn’t a chronic disease in the same way as Arthritis or heart disease.  Mast cell disease is much more akin to an acute immune event, like having strep throat.  Our mast cells constantly think we’re being attacked by a foreign invader and mount a response, including the release of inflammatory mediators.  The problem being our mast cells are so twitchy they can do this to just about anything, which means we have many acute attacks (sometimes several a day) and our body hasn’t recovered from the last one before the next one arrives – a bit like being stung by a bee over and over and over again.  And if eating anti-inflammatory foods has no effect on an acute event like strep throat I’m unconvinced it has any effect on the multiple acute events of MCAD or Mastocytosis, although I could be wrong (I often am 😉 ).

There isn’t even much agreement on what constitutes an anti-inflammatory food or diet in the first place – I got as confused reading about conflicting anti-inflammatory foods as I did about conflicting low histamine foods!  Dairy foods are widely thought of as being inflammatory, yet this review of all the research to date found no such link (in fact one of the studies concluded just the opposite, that dairy lowered inflammation).  You would think something like blueberries would be considered highly anti-inflammatory, but actually fruit contains high levels of sugars, which spike insulin, which is inflammatory.  It’s actually really complicated!

We’re all different, with different genetic susceptibilities and make-ups and consequently we react to foods differently.  For example over 90% of some East Asian communities are lactose intolerant, whereas only about 5% of people of Northern European descent are lactose intolerant.  Around 50% of Asians have a toxic reaction to alcohol, which is virtually unheard of in Northern Europeans (we just drink wayyy too much and make idiots of ourselves instead!).  It stands to reason that different people will have different reactions to foods based on their genetic make-up.  So while one person finds eating certain foods makes them feel brilliant, another person eating the same foods will find no difference whatsoever, and I don’t see why so-called anti-inflammatory foods would be any different.  There is no “one size fits all” diet.

It makes me laugh when I read comments online about people who’re following an anti-inflammatory diet (which usually excludes dairy and grains, who are so evil I have to wonder how we’ve managed to grow the world’s population to over 7 billion with a diet rich in them) and say how well they now feel, how much energy they have and that they’ve lost 2 stone (28lbs) in weight.  What the hell were they eating that they were 2 stones overweight in the first place?!  Obviously a pile of crap, so I’m not surprised now they’re eating fresh fruit and veg and some decent protein they feel better.  It’s not rocket science.  If I ate a diet which caused me to lose 2 stones in weight I’d be under 6 stones (84lbs) and probably in the hospital – losing weight would be unhealthy for me.

The whole thing is a lot to get my head round.  I’m not dismissing anti-inflammatory diets in any way – most so-called anti-inflammatory foods are plant based in origin and eating any plant based food is going to be good for you in all sorts of ways.  But neither can I say categorically which foods are anti-inflammatory and which aren’t, or how any food works on inflammation in the body.  And from what I can gather neither can anyone else (though I’m sure I’ll have all sorts of comments telling me this person or that person has the definitive list of anti-inflammatory foods!).  I personally have never had acne (in fact I’ve never had a single pimple in my whole life), or been overweight (despite zero exercise for 20 years), or had high blood pressure, or had any abnormal blood results for inflammation so if I do have significant inflammation it’s manifesting itself in fairly hidden ways but that’s not to say it’s not a problem for me.  I don’t know.  I don’t know lots of things and the science so far doesn’t sway me one way or the other.  I’ll just continue to eat a balanced diet, containing as wide a range of foods as my reactions will allow so that all my bases (not just inflammation) are covered.