Category Archives: Medical & treatments

Research trends

I’ve mentioned recently my frustration at the current research trend in the M.E. world to focus on energy production when, as a sufferer, I know that the ‘fatigue’ (for want of a better term) I experience is merely a symptom of immune activation not the root cause of my disease. Researchers have been studying energy production, in particular the mitochondria, as a cause for M.E. for over 20 years now and still haven’t found anything, which leads me to conclude there is nothing to find.  I’m not suggesting that mitochondrial dysfunction isn’t part of the disease picture but it’s definitely not the cause.  I wish these people would talk to patients more, especially we old timers who’ve lived with the illness for decades!

I’m equally unconvinced by the current trend to put every ailment known to man down to gut issues (SIBO, flora, bacteria etc) – it just feels like the current ‘hot new thing’ in a very long line of ‘hot new things’ on which to pin disease.  My Dad excitedly kept an article out of his newspaper for me this week which touted “answer to chronic fatigue syndrome found in the gut” and, much as I love him, I just sighed.  Here’s the thing: most cases of M.E. start with some kind of viral or toxic event (OP poisoning, vaccinations) but the event is different in all of us – mine was a tummy bug, yours might have been glandular fever, someone else’s a Hep B vaccine.   If we’d all started with a tummy bug then I’d be much more open to the disturbed gut theory, but we didn’t.  The one thing we share is immune activation, so for me the answer has to lie in the immune system and in particular its response to viral or toxic trauma.  As I’ve said before, if researchers studied why people with the flu are so weak and exhausted they can barely get out of bed they’d go a long way to finding out the cause of M.E.  In fact, it gobsmacks me that no-one has looked at that before now!

No offence to my American friends, but there is a mould trend going on in the States with everyone convinced that mould is the root cause of their issues and it makes me want to chuckle.  Northern England is wet for 10 (sometimes 12) months of the year, humid in summer, we mostly live in houses which are at least 100 years old and inherently damp, so I’m sure mould is everywhere.  We couldn’t escape it if we tried.  Yet not every Brit you meet is sick and we don’t have a larger M.E. population than any other country as far as I’m aware.  Obviously rampant mould growth, where you have black stuff growing on your ceiling, is hazardous to health and must be dealt with but other than that we in the UK don’t give mould a second’s thought – it’s been around a lot longer than we have and as a species we’ve managed to survive.

I’m just as cynical about the current inflammatory trend.  Inflammation, it seems, is everywhere and is causing total havoc.  Only of course it’s almost impossible to measure inflammation or to say, if inflammation is present, why it’s there and whether it’s a good thing or a bad thing.  When we cut ourselves the wound is immediately inflamed which is a painful, but absolutely necessary, part of our body’s response and vital for healing.  And before anyone comments, yes I know there’s a difference between acute and chronic inflammation but who’s to say chronic inflammation isn’t just as protective as acute?  It’s got to be there for a reason and we’d do better to find out why our bodies are enlisting our inflammatory response, rather than blaming the inflammation itself.

Going off-topic slightly, the trend of foods purportedly giving you every disease from cancer to Alzheimer’s drives me insane.  We have no idea what causes Cancer and even less idea what causes dementia, so for anyone to say “burnt sausages give you cancer” or “broccoli reduces your risk of Alzheimer’s” is absolutely absurd and makes me furious.  In fact, I’d go as far as to say researchers who tout this nonsense should be prosecuted.  The same goes for anti-inflammatory foods.  If we have no accurate way of measuring inflammation, how do we know what foods affect it?!

There have been articles in the newspaper this year saying “exercise staves off dementia” and “lack of sleep increases risk of dementia” and I think “what a crock of shit!”  My Dad, who is 78, still walks 8 miles a week up a mountain and, as a former marathon runner, has exercised vigorously his entire life.   He’s never had insomnia and sleeps 9-10 hours a night without a problem, yet has dementia.  My Mum, on the other hand, hasn’t exercised since she was a child and wakes at least twice a night every night, yet she is totally mentally on the ball (when she’s not drunk!).  All these articles do is play on people’s emotions.  We don’t have a clue what causes Cancer or Alzheimer’s and that lack of control scares us, so we focus on what we eat or how much we exercise because those are two things we can control and it makes us feel better.

I’m no psychologist, but much of the information currently touted as being bad for our health, or good for our health, is environmental – sleep, exercise, food and living conditions.  In other words, all things we can control.  We’re extremely fearful of the fact that Alzheimer’s or Cancer might be viral, bacterial, or genetic, or even worse some novel new thing we as yet know nothing about, and therefore outside of our control.  We’re fairly arrogant us humans and think that we have power over our bodies, when in fact life is mostly just random and shit simply happens.  If keeping mentally alert staves off Alzheimer’s how come author Terry Prachett developed it in his 50s?  If the phytoestrogens found in soya stave off breast cancer how come soy munching vegetarian Linda McCartney died from the disease?  How come my Mum, a lifelong smoker, couch potato and current alcoholic, is nearly 80 and has never had cancer and her non-smoking, tea-total, bike riding sister died from it?  None of it makes sense and that’s the very thing that scares us the most.

Normal test results

I’m the healthiest sick person you’ll ever meet.  Despite having Spinal Stenosis, MCAD and EDS from birth, M.E., Histamine Intolerance, Endometriosis and Adenomyosis 98% of all my test results have come back “normal”, at least according to my Doctors.  It will not surprise you that my response to that is “knickers!”.

When I was 11 I was climbing in some outbuildings and fell from the first floor onto the bonnet of a car, after which I developed back pain.  For the next 5 years I went backwards and forwards to the hospital who could find no reason for my symptoms.  X-ray results were “normal” and eventually I was told I was “attention seeking” and needed to see a shrink.  I refused and demanded a second opinion from an Orthopaed at a decent hospital 90 miles away (I was bolshy even at 16 😉 ).  Within 48 hours of being admitted they discovered I had been born with rare congenital spinal stenosis and urgently needed a laminectomy.  The fall wasn’t the cause of my back issue but had just aggravated a pre-existing condition.

This was my first experience that Doctors aren’t Gods and sometimes get it wrong and over the coming years I was to discover that they get it wrong more often than any of us would like.

It’s only in the past 5 years or so that NHS patients in the UK have been given access to their test results.  Historically, GPs would take loads of blood, not even tell you what you were being tested for and the results were sent back to the GP who only ever rang you if something abnormal was discovered.  But a GP’s idea of “normal” results and my idea of “normal” results seem to differ.

As I’ve discussed recently here on my blog, at the tail end of last year I started having symptoms of anaemia so asked my GP to check my iron levels.  They came back 1 point above the very bottom rung of “normal” (normal range 17-160 according to my lab sheet, and my result was 18), so my GP considered that fine.  Only of course it wasn’t fine because I was having symptoms.  I took it upon myself to start some supplements and within a week the pallor, exhaustion and daily dizziness I’d had for months vanished.  But if hadn’t gone to the surgery to request a print-out of my results and seen that my levels were low my GP would have just said everything was “normal”, I wouldn’t have tried the supplements and would have continued to feel like death warmed up.

When I saw Dr Seneviratne for my histamine/creatinine test it was high but within the “normal” range (normal is 34-177 and mine was 140).  However I’d been on a low histamine diet for 4 months at that stage, which one would hope would lower my histamine load and therefore skew the result, plus was symptomatic (at the time of testing my bum was covered in hives).  So thankfully Dr S still diagnosed me with “probable” MCAD because my history fairly conclusively suggested it.  But not all Doctors think like that – they see “normal” test results and rely on those, even when all the evidence is pointing towards there being a problem.

I’ve had severe gynae pain since the day I started my periods and over the years have had various tests and scans all of which were “normal”.  Well, apart from the fact my first ovarian scan showed a 2cm cyst which I was told was cyclical (they know this how?!) and 12 years later my second ovarian scan showed a 5cm cyst.  Turns out I have polysystic ovaries and due to my endo some were blood filled and when they burst caused excruciating pain and adhesions :-/  My first pelvic MRI at my local hospital showed absolutely nothing untoward, yet an MRI at a specialist endo centre six months later showed extensive endometriosis which even I could see on the scan!  So it turned out that the excruciating pain I’d lived with for the better part of 40 years wasn’t “normal” after all and I needed an urgent hysterectomy.

Anyone with Hypermobile Ehlers-Danlos Syndrome will tell you how painful and disabling the condition can be, yet nothing shows up on tests.  Genes and skin are normal, as are scans and x-rays.  Before I suspected hEDS I was told by medical staff that I was just “sensitive to pain” which made me feel like a total loser – little did they know I lived with pain most days that would have a healthy person reaching for the Vicodin and I did it without so much as a murmur, so far from being sensitive to pain the opposite was, in fact, true.

Here’s the thing I wish Doctors took more on board – if a person is having symptoms there is a problem, even if test results look “normal”.  I wish they’d listen more to what we’re telling them, take a full history and trust that we know our bodies better than they do.  What is “normal” for a 6ft 4″, 16 stone, male, thirtysomething rugby player might not be “normal” for a 5Ft, 7stone, teenage girl.

Back pain at the age of 11 is not “normal”.  Gynae pain so severe you’re curled up in the foetal position every month is not “normal”.  Fainting is not “normal”.  Widespread pain is not “normal”.  Seizures are not “normal”.  Fatigue which puts you in bed by 4pm every day is not “normal”.  Collapsing after every meal is not “normal”.  Flushing is not “normal”.  Daily nausea is not “normal”.   I don’t care that all my tests indicated nothing was  wrong, because something clearly was and it wasn’t something trivial to cause that much havoc.

My cynicism towards the medical profession is now legendary – that’s what comes of being fobbed off or 40 years that all is well.  In the end, I had to guess what my diseases were and inform my Doctors, who then did the relevant tests which, surprise!, came back not normal in any way 😉  I trusted my instincts, even though when I was younger I didn’t have enough confidence to challenge my Doctors.  I know there are some people who are hyper-vigilant and obsessive and who think they have some dreaded disease from every little ache, pain and niggle (I’ve met some of them online!) but I know my personality and know that I’m not a drama queen or someone who focuses abnormally on my body (again, the opposite is true and I actually ignore symptoms when I really shouldn’t!).

These days I’ve gained a fair bit of knowledge about my body and I know what’s normal for me and what’s not.  If I’m not happy with a consultation I’ll research the best doctor to see and request a referral even if it’s hundreds of miles away (which is my legal right).  I request a copy of my test results and will push for treatment or further testing if I think it’s needed.  After all, I’m the one who has to live in my body and suffer my symptoms, not my Doctor.

 

Holes in diagnosis

I was diagnosed with Benign Joint Hypermobility Syndrome in 2010 when I was 43.  I scored 8/9 on the Beighton Score and had other clues such as “mildly” stretchy skin, mildly blue sclera in my eyes, life-long bowel issues, an overcrowded mouth and high roof arch, migraine, heart murmur, mild scoliosis in my spine, congenital spinal stenosis, easy bruising, skin which scars easily, skin which tears easily, a positive Gorlin’s sign (ie being able to touch tongue to nose), chronic fatigue and widespread pain for which no reason could be found. My Consultant said she only diagnosed Ehlers-Danlos Syndrome when there was “significantly stretchy skin” which I don’t accept as correct.  With a family history of the symptoms of EDS (which she didn’t ask about) and my collection of symptoms it was clear I have Ehlers-Danlos Syndrome and whilst I accept I don’t have freakishly stretchy skin, to me my skin involvement is not “mild”.

Photo of stretchy neck skin

Stretchy neck skin

My skin in general is a bone of contention to me.  As well as weird lumps, bumps, moles, pigmentation and scars I’ve had some strange skin on my knees and tops of my feet my entire life, yet when I’ve mentioned it to Doctors in connection with my Ehlers-Danlos it’s just been dismissed.

It doesn’t itch and no matter how much moisturizing cream I’ve ever put on it never looks any different.  According to Doctors it’s not eczema or psoriasis but then they don’t tell me what it is.  Needless to say I don’t ever wear dresses above the knee :-/  To me it points towards Classical EDS but then I’m not an expert so what would I know?

At the time of my Joint Hypermobility diagnosis I’d never sub-luxed or dislocated a joint, didn’t have GERD or a hiatus hernia to my knowledge and had no idea I also had mast cell disease.  However, within 2 years of diagnosis my mast cell disease was potentially life-threatening, I had walking pneumonia from undiagnosed silent reflux (which is now not silent in any way!) and had subluxed 6 joints.  When the Powers That Be say Ehlers-Danlos is not progressive IMHO they have no idea what they’re talking about.

When children and adults under 30 are diagnosed with Joint Hypermobility Syndrome I wonder if they, like me, actually have EDS and it just hasn’t progressed to the stage of meeting the criteria.  Of course, not everyone with JHS has EDS but as no data is kept it’s impossible to know how many younger people’s disease goes on to be re-defined as Ehlers-Danlos.

Another part of my diagnosis which with hindsight was sadly lacking is the fact that I was offered no genetic testing.  I personally think this should be compulsory for all suspected EDS patients, especially if there is a strong family history.  My brother is 6ft 2″, has eyes which slant downwards at the corners, much stretchier skin than me, had ‘growing pains’ in his legs as a child and had to stop a promising professional football career due to knee problems.  He has flat feet and a high roof palate.  As a child he used to ‘pop’ his knuckles and do robotics (a dance craze at the time) because he was hugely flexible.  Now in his early 50s he’s so stiff he can barely move, yet he’s never been ‘ill’ like I am or had any of the bowel issues, pain or fatigue that I do.   He definitely has Marfan’s traits but luckily for him they don’t seem to have affected his life to any extent.  As a child he had chronic bronchitis which was put down to a dust mite allergy (no idea how they worked that out as he was never given skin prick testing) but he apparently grew out of it.  He’s still allergic to dogs and horses though, oh and eggs.  Lots of children have allergies and some kids do grow out of them, but bearing in mind our family history of mast cell disease I do wonder if there is some connection.

My Mum was hugely flexible as a child.  She has soft, stretchy skin which scars and bruises easily.  She has pectus carinartum (aka pigeon chest) which is caused by defective connective tissue which holds the ribs to the breastbone.  She’s had reflux for 30 years and had lost 25% of the bone mass in her pelvis due to osteoporosis by the time she was 54.  She had a collapsed lung for absolutely no reason in her forties which is found in some types of EDS but not usually the hypermobile type, and horrible varicose veins which developed in her twenties.  She’s had 3 fatty tumours removed from her skin and has very wide stretch marks due to pregnancy.  She also has dupuytrens contracture in her hands, which is due to defective collagen.  I can find no data to connect dupuytrens to EDS, but as there is barely any statistical data on EDS to start with it’s not surprising that no-one is looking for a link.  It seems too coincidental to me that someone with EDS has a genetic, un-connected connective tissue disorder of the hands.  She has obvious mast cell disease, though not as severely as me.

Dupuytrens contracture

So my family history seems to be a mix of Marfans traits, Classical EDS traits, possibly vascular EDS traits and Hypermobile EDS traits.  Chuck in MCAD and other inherited diseases (familial essential tremor, dupuyrens contracture, early onset osteoporosis – all through the maternal line) and to me genetic testing should have been carried out.

I don’t know whether at this late stage to push for genetic testing or not.  I’m not sure what it would achieve, however it might help my future disease management if it shows I have classical EDS traits as well as hypermobile.  It would also obviously be beneficial to find out if my Mum’s collapsed lung was connected to her EDS or not and whether unexpected vascular events are something I need to be concerned about.

I get sooooo fed up of being my own Doctor and at having to fight for every blummin thing.  What happened to medical staff looking after me and telling me what I need, instead of the other way round? 😦

Blood Results

I had to go to the Surgery today to pick up my Famotidine prescription, so while I was at reception I asked if my recent blood results had come back.  They had, so I requested a print-out and there is some great news and some mildly not-as-great news.

The good news:

  • I only have a 1.3% change of having a heart attack or stroke in the next 10 years.  You can do your own QRISK test online here.
  • My inflammatory markers (Serum C reactive protein) are low at <2mg/L (normal is anything under 5mg/L).  Bizarre being as though I have chronic gastritis (an inflammatory stomach disease), MCAD (which causes chronic inflammation) and am permanently injured due to my EDS (injuries cause inflammation).  My C reactive protein levels have always been low, which is great if not a true predictor of what’s actually going on inflammation-wise!
  • Liver normal.
  • Urea and electrolytes normal.
  • Blood sugar is fine.  HbA1c level is 32, which equates to an actual blood sugar level of 5.5% (anything under 48/6.5% is normal).
  • Folate levels are good at 4.7ug/L (anything above 2.5ug/L is normal).
  • B12 levels are good at 378ng/L (normal levels are between 197-771ng/L).  Obviously as a pesco-vegetarian it’s important to monitor B12.
  • Full blood count is normal.

The not as good news:

  • My Vitamin D levels are normal but at the low end of normal.  I live in the northern hemisphere and we’re at the end of winter, so this is to be expected.  I do try to keep my Vit D levels up by eating dairy products daily and getting outside for at least 30 minutes every day of my life with Bertie, but we don’t have much sunshine here in the north of England so it’s easy for Vit D levels to be low.  It’s not something I worry about in any way and I don’t usually feel any worse in winter than I do in summer.
  • I have low iron, which again comes as no surprise and is the reason I went for a blood test in the first place.  My serum ferritin is 18ug/L (normal is 17-291ug/L) and, coupled with my 5 risk factors, I need to see my GP re iron deficiency anaemia.  Sadly I can’t get an appointment with my GP until 22nd March (!) so in the meantime I’ll buy some liquid iron from the supermarket and try that (liquid iron has less iron in it than most of the tablets, so tends not to cause constipation though it does take longer for iron stores to increase).
  • The biggest shock was that my kidney function is lower than it should be for my age at 73 (between the ages of 40 and 59 it should be in the 90s).  A GFR (Glomerular Filtration Rate) of 73 is classed as stage 2 chronic kidney disease, although doesn’t require any treatment.  I would have completely freaked out when I read this if my best mate, who is 8 years younger than me, hadn’t had the exact same result recently.  Her GP said it was nothing to worry about, though you do wonder why we both have reduced kidney function!  My Mum has a GFR of 45 but her GP isn’t bothered and says no treatment is needed, so it seems unless your GFR is 1/3 of normal it’s not something to be concerned about?!

In a way I’m glad my iron has come back low because it explains the symptoms I’ve been having for the past few months and hopefully I can do something about it (makes a change!).  Having been pesco-vegetarian for nearly 30 years this is the first time my ferritin levels have ever been below normal, so it just shows the impact a reduced diet or taking certain medications can have and also the extra burdens placed on our bodies during Menopause.

Anaemia

I’ve been feeling really washed out the past couple of months and my get up and go has got up and gone.  Both ME and EDS cause “fatigue” but I’ve had both for so long that I know what that exhaustion feels like and my current waffy-ness feels different.  I’ve also been dizzy……a lot.  I do suffer from dizziness as part of my existing conditions, but only for the odd day now and then and it’s usually so severe I can’t get out of bed.  My current dizziness is milder but ever present and each time I turn my head the world tilts slightly on its axis.  Plus I’m not sleeping.  I’ve had insomnia for over 2 decades but again this feels different and I just have a niggle that “summat’s up”.

Of course I am peri-menopausal and fatigue, dizziness and insomnia are simply part of the bag for many women.  But then so is anaemia especially if your periods are heavy, and mine are definitely heavier than they used to be.  There are various types of anaemia, but in menstruating women iron deficiency anaemia is the most common so I made an appointment to see the nurse today to get my bloods checked.

I have just about every risk factor for anaemia going:

1.   Peri-menopause/Menopause

Any menstruating woman can be at risk from anaemia, particularly if she has heavy periods.

2.   Endometriosis

I’m not just bleeding from my uterus every month, I’m also bleeding into my pelvic cavity because I have endometriosis.

3. MCAS

Anaemia is the most common issue affecting red blood cells in MCAS patients.  See Lisa’s excellent post written on this issue over at Mastattack.org

4. Gastritis

Any type of inflammatory stomach or intestinal disorder can cause anaemia, eg. gastritis, ulcers, diverticulitis, crohn’s disease, colitis, coeliac disease, GERD (ie acid reflux).

5. Drugs used to treat GERD

PPIs, H2 blockers and antacids can all interfere with iron absorption and I have been swigging Gaviscon and Rennies recently like they’re going out of fashion on top of taking an H2 antihistamine.

4. Diet

I’ve been pesco-vegetarian for nearly 30 years.  Before getting Histamine Intolerance I was very careful to eat a wide range of high iron vegetarian foods but since getting HIT and having to eat low histamine I’ve had to remove many of these from my diet, eg. spinach, soya beans, kidney beans, dried fruit, cashew nuts.

Diet deserves special mention.  People with ME, EDS, HIT and/or mast cell diseases are often on restricted diets of one kind or another.  Here in the UK we hardly ever get to see a Dietician, so are left to try and work out our food issues alone.  We often don’t have the skills or knowledge to decide if we’re eating enough of the right foods to give us all the vitamins and minerals we need, so it’s really important to have our bloods checked once a year just to make sure we’re not deficient (I was shocked to learn today that I hadn’t had a full blood work up since 2014 despite all the various issues I’ve had in the past year or two!).

I won’t get my results back until early next week, so I’ll keep you posted.  For those of a religious disposition please pray I’m not anaemic and don’t need iron tablets.  My poop is the only thing in my entire digestive tract which is currently normal so the last thing I need is to not be able to go-potty for days on end! 😉

Tootsie Trouble

For 4 months now my feet, hips, pelvis and lower back have been dreadful.  I’ve had niggly ball of foot pain before but nothing like this – trust me when I say it’s sodding agonizing to walk when the soles of your feet hurt!  My hip sockets have also been painful….again.  In 2014 I was diagnosed with Greater Trochanteric pain syndrome (I seem to collect syndromes like other people collect rare china!) and spent 9 months on crutches ‘resting’.  It showed up again in the Autumn of 2016 like an unwanted ex and my crutches came out of storage.  Last time my right hip/leg was the most sore and this time it’s been my left (my pain likes to move around just in case I get bored). My SI joint is also playing up after being really good for a couple of years now.

I had no idea what had set my lower body off and when you don’t know the cause of something it makes it hard to cure.  I instinctively knew, however, that my feet were the cause of my hip, pelvic and SI pain so I tried 4 different kind of shoe insoles to see if they would help.  This is on top of the half a dozen I’ve tried over the years from my Podiatrist, including custom made moulded insoles which actually made my feet worse, WTF?!  In desperation, in December I spent £80 I didn’t have on some G8 insoles, which are used by cyclists.  They come with customizable arch supports with 5 different heights which you can move around – an ingenious idea.  They felt great but sadly didn’t help my foot pain.  I even tried metatarsal pads, which were seriously uncomfortable and didn’t help either.

The only thing that had changed in the Autumn of 2016 was that I’d bought myself some posh new wellies.  The Lake District is renowned for its rainfall and I live in wellingtons about 10 months of the year.  For the past few years I’ve had Dunlop Blizzard, which are really comfy and snuggly warm due to their fur lining, but they only last a couple of years before they either split or the lining disintegrates.  So this time I went for some stupidly expensive Muck Boots.   They are the warmest wellies I’ve ever owned, look trendy, are totally waterproof (as against water resistant as cheaper neoprene wellies tend to be) and even with my 4 degree insoles in felt really comfy, if slightly snug on my right foot.  I also thought that, being more fitted on the leg, they would be more supportive for my ankles which did tend to flop around in my previous wellies.  I loved my Muck Boots but it turned out the feeling wasn’t mutual.

As my wellies were the only thing I’d recently changed, I went back to my old Dunlop Blizzards just to see if made any difference and to my absolute amazement within a few days my feet were less painful.  I’ve now been back in my Dunlops for 3 weeks and both my foot and hip pain are 70% improved (my SI joint is still niggling away but you can’t have everything in life!).  I’m gobsmacked that the Muck Boots, which felt totally fine, have caused such havoc.

Regular wellies, like my Dunlops, have wide feet in which your tootsies tend to slop around a bit.  I have slightly wide feet (size D) when they’re measured and have to accommodate my insoles, so do need plenty of room in my footwear.  Muck Boots are tight fitting on the leg and, unlike regular wellies, are also narrow in the feet fitting more like shoes.   Although they felt comfy enough I think that when I walk my stretchy foot ligaments cause my feet to splay out considerably and there simply wasn’t enough room for that in the Mucks.  Like my Podiatrist said, 1 or 2mm makes a massive difference to people with EDS where it wouldn’t bother the rest of the population.

I now have a £90 pair of brand new size 4 (EU 37) Muck Boots and an £80 pair of size 4 G8 insoles for sale if anybody fancies them!

Abdominal pain

I’m starting to get worried about my gut.  Actually, that’s a lie.  I’ve been worried for a while now.  For several months I’ve had chronic abdominal pain.  At first it came and went and, though it was unpleasant, it didn’t bother me too much.  I get all sorts of random symptoms that come and go and they eventually settle down.  Not this time.  The pain, I have to admit to myself, is getting worse.  It’s constant and for 3 months now it’s been waking me up from sleep.  Last night was awful and I am a wreck this morning.

I am in pain from the middle of my oesophagus to my backside.  My back is in spasm from my shoulder blades to my tailbone.  I feel permanently sick and, though I get hungry, I’m full quickly.  The only good news is that my poop is fine, still huge, normal colour, no signs of blood, no constipation or diarrhea and I go nearly every morning after breakfast.  It is, however, about the only thing in my entire digestive tract which appears normal.

I know my oesophagus and stomach are being eroded by acid but when I can’t take H2 antihistamines or PPIs treatment for my chronic GERD is almost impossible.  High dose Gaviscon does help but doesn’t eliminate the problem.

I have so much wrong with me that the abdominal pain could be thirty different things: my MCAD, inflammatory bowel disease such as diverticulitis or colitis, gallbladder issues (my Mum had hers removed in her forties after 10 years of indescribable stomach pain), nerve impingement, hernia in the bowel wall, stomach ulcer……the list is endless.  It could even be a back issue and it’s referred pain or it could be down to my endometriosis adhering to the bowel walls.  Trying to get to the root cause of the pain is going to be a bloody nightmare and treating it with my drug allergy history probably impossible.

Ehlers-Danlos can cause a whole range of gut issues.  MCAD obviously causes gut pain.  Many people with M.E. have gut problems, the reason for which can usually never be found and get put down to “IBS” (a non-diagnosis if ever there was one).  Endometriosis can also affect the stomach and bowel.  It could be all four or totally unrelated and something else entirely – how on earth is the doctor going to know what’s causing what?!

The pain isn’t worse when I eat.  In fact, it’s worse during the night and first thing in the morning when my stomach and bowel are fairly empty, work that one out!  It’s proper getting me down now, especially as it’s affecting my sleep 😦

Please can I not have any comments telling me to cut out dairy or gluten or do a FODMAP diet.  If only my health problems were that simplistic.

I think I’m going to risk taking some antihistamines and see if I can tolerate them.  I started reacting to both H1s and H2s last year so stopped them, but it may be that now I’ve had a break I can tolerate them again (I started reacting to Gaviscon in 2015 but am taking it again fine this year).  If antihistamines help at least I’d know it’s probably my MCAD that’s playing up (I am super itchy atm).  I’m also still trying to pluck up the courage to try a different brand of PPI for my acid but am such a chicken when it comes to trying new meds after having so many awful reactions.

I suppose in some ways I’ve been lucky.  I had no serious gut issues until I was 45 which, considering all my illnesses can cause stomach problems, is fairly miraculous.  I’d better make an appointment to see my GP (for which I may wait 6 to 8 weeks), who will refer me to Gastro at the hospital (for which I may wait 4 to 6 months).  So hopefully I might get to see a Consultant by October!